Structural studies of vinblastine alkaloids by exciton coupled circular dichroism.
نویسندگان
چکیده
SCF-CI-dipole velocity MO calculations have shown that the bisignate circular dichroic curves of vinblastine/vincristine alkaloids at ca 210 and 220-230 nm are due to exciton coupling between the indoline and indole moieties. Furthermore, a combination of X-ray crystal structure data with MM2 local energy minimization provides a convenient means for estimation of the preferred solution conformation.
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ورودعنوان ژورنال:
- Phytochemistry
دوره 40 6 شماره
صفحات -
تاریخ انتشار 1995